Tuesday, June 9, 2015

Bacteria that can help fight cancer

World Hot Topics Blog

Bacteria that can help fight cancer
New York, June 9 (IANS) A toxin secreted by a water and food-borne bacterium that can cause lethal infections in persons with liver disease, has the potential to prevent the growth of tumours, says a new study by Northwestern Medicine scientists.

"A toxin protein from the bacterium Vibrio vulnificus can inhibit tumour cell growth by cutting the protein Ras," researchers said.
"Ras is important for cell proliferation in cancer, so the toxin could potentially be developed as a treatment for different types of tumours," said one of the researchers Karla Satchell, professor in microbiology-immunology at Northwestern University Feinberg School of Medicine in the US.                  World Hot Topics Blog

"The bacterium uses the MARTX (multifunctional-autoprocessing repeats-in-toxin) toxin protein to inactivate Ras, increasing its own virulence and allowing it to spread throughout the host," the study said.

"It has been known that Ras has a role in cancer development and targeting Ras has been one of the hardest challenges of cancer research and drug discovery," Satchell said.
The findings appeared in the journal Nature Communications.

This World Hot Topics Blog is Originally from here :

https://in.news.yahoo.com/bacteria-help-fight-cancer-100404790.html

Monday, March 2, 2015

Toronto tunnel mystery solved, say police

World Hot Topics Blog

Toronto tunnel mystery solved, say police

Ottawa (AFP) - Toronto police said Monday they now know who dug a tunnel near a major sporting venue in the city -- a mystery that has been a source of widespread speculation and conspiracy theories.

In a statement, police said two young men stepped forward to acknowledge responsibility after authorities made a public plea for help to determine its purpose.

"The two men told investigators they built the tunnel for personal reasons," police said.

They added that their account has been verified, and that authorities "are satisfied there was neither criminal intent nor any threat to the people or city of Toronto." World Hot Topics Blog

The tunnel, which also is situated near Toronto's York University, was discovered by a wildlife official walking through woods. He spotted a piece of corrugated metal on the ground, lifted it up and found a passageway.

It was more than six feet (1.8 meters) high, almost three feet (0.9 meters) wide and about 33 feet (10 meters) long, and was hidden in a densely wooded area of the city, "well off the beaten path," deputy police chief Mark Saunders told a press conference last week.

Image released on February 24, 2015 by the Toronto Police shows the inside of a tunnel found near Yo …

Had it continued, the tunnel would have exited on the other side of a hill overlooking nearby tennis courts and a sports facility that will host the Pan American Games in July. World Hot Topics Blog

Its discovery provoked widespread speculation about who built it and why. 

National security officials were alerted, but suggestions the tunnel posed a threat were quickly dismissed. Police also said it was not a drug lab.

Online sleuths and media suggested it could be a survivalist's fallout shelter, a prank, or a niche home in Toronto's red hot condo market.

American horror writer Stephen King weighed in that it was likely a wormhole built by aliens.

Before it was filled in, the second in command of Canada's largest city police force described the interior of the tunnel as humid and warm.

The walls were lined with plywood and reinforced with wood framing. It was lit by an electric generator and a sump pump was used to keep it dry.

Police also found a bucket and pulleys and a wheelbarrow likely used in the dig.

As well, a rosary with a poppy attached was nailed to an inside wall, and discarded food and beverage containers point to someone having used the tunnel over the winter, Saunders said.

This World Hot Topics Blog is Originally from here :
http://news.yahoo.com/toronto-tunnel-mystery-solved-police-161413862.html

Wednesday, July 16, 2014

Ayurveda And Multitasking - World Hot Topics Blog



 World Hot Topics Blog

Ayurveda And Multitasking 

Multitasking is a key word for todays lifestyle. Each of us do it with our thoughts. 

is it really helpful for our body &  health ?

What exactly multitasking mean? 

How does it affects our health? 

Let's solve all this in Ayurveda way.

As it indicate, multitasking means doing more than one work at a time. 

Usually this refer to have more thoughts at a single time.

Thought is created by brain. Brain is located in skull, at upper most part of body. Brain works on glucose & oxygen supplied by blood. This blood is supplied by heart.

So, when we have a single thought brain is working in single way. As thought is brains own work it did not disturb its rythum. Heart too supply in a single rythumic way. This is a ideal situations for these vital organs. Nobody get hurts.
But, at multitasking, having more thoughts, brain have to work fast. Brain needs to work on several levels. At this point brains own rythum gets disturb. It requires more energy, so heart has to pump the blood towards the brain, against the gravity, which again requires more energy to heart. This all disturbed the working rhythm of brain & heart.

Surely, individual can't get hurt in a single incident. But because of this disturb rhythm these vital organ, VATT dosha get increase. Resulting in many unwanted sings like,

Loss of concentration
Head ache
Memory loss
Harmonal changes
Short temperness
Hyperactivity & Hyperness 
 World Hot Topics Blog

In many more cases Multitasking is a root cause for a disease. 

So, how can we avoid it.

First accept the thing that multitasking hurts. 

As you accept it, you will start to avoid it. 

In Ayurveda, there are two ways for it.

1) To improve strength of brain & heart with medication, good food, & by changing lifestyle.
2) To concentrate on single topic at a single time. If a second though comes in note it down, but don't keep in brain. Finish the first one & then go to second. 

This is called Switch on, Switch off method. This method looks difficult, but after some practice, you can enjoy the power of your brain. 

Hope this Helps to all busy Multitaskers 


 World Hot Topics Blog



For futher details Contact : 
Dr Amogh Deshpande
Ayurved Dep.Hardikar hospital
Shiwajinagar Pune – India
Mobile : 9860097753

Tuesday, February 11, 2014

5 ways to survive Your first freeze.




World Hot Topics Blog

 5 ways to survive Your first freeze.

Editor's note: Charles W. (Chuck) Bryant is the co-host, with Josh Clark, of Discovery Channel's 'Stuff You Should Know.' The pair has released nearly 600 episodes of their award-winning show since 2008.
(CNN) -- If you're from, say, the Midwest or Northeast or Alaska, dealing with the cold is not only a way of life, but also a point of pride: You can take care of yourself, and you're not shy about pointing it out. But, as evidenced by this week's "polar vortex," cold weather can barrel through many parts of the country — Georgia, Florida, Arkansas — where people aren't used to sub-freezing temperatures.
There are some true life-threatening scenarios, like a car breaking down on a rural stretch of wintery road (always pack a blanket), but it can be dangerous even in your own home if you're caught without the necessities you need to keep warm, and this is especially true for the elderly.
If you're in a part of the United States new to this kind of severe weather, here are some suggestions to help you help yourself.
 World Hot Topics Blog
 1: Wind chill can kill
Wind chill is the effect of moving air on exposed skin, a term coined by Antarctic explorer Paul Siple in the late 1930s to help describe how wind figures into heat loss. He experimented with wind chill's effect by timing how long it took to freeze water in varying degrees of wind strength. If you're not used to bitter wind chill, realize that you need to take it seriously when preparing for any outdoor activities. Skin exposed for five minutes in below-zero wind chill conditions can get frostbite. Longer can do worse.
Two University of California at Berkeley economists found that deaths related to cold reduced the average life expectancy of Americans by a decade, if not more. In countries where people were exposed to 10 or fewer days a year, the death rate was substantially higher than in countries with at least 90 cold days a year.
Additionally, cold weather can leave us without our thinking caps, willing to do whatever it takes to warm up. This can indirectly lead to unexpected fatalities because of accidents relating to carbon monoxide poisoning and house fires.

 World Hot Topics Blog

 2: Hypothermia and layering
Hypothermia -- when your body temperature falls to 95 degrees F -- is a grim possibility if you're facing the cold without power, and layering your clothing is your best first defense against it. If you're experiencing slurred speech, stiff joints, a loss of coordination, uncontrollable shivering, loss of bladder control, puffy face or mental confusion, you could be suffering from hypothermia, which can be fatal. To combat this, get yourself into a warmer environment as soon as you can. Cover yourself with any items you can find -- blankets, sleeping bags, pillows. Just as you layer your upper body clothing, you should also layer what you have on your feet. Try a thin pair of nylon, silk or wool socks for starters -- then layer with additional wool socks. If you think a loved one is suffering from hypothermia, you should handle that person with great care, as the condition could make it easy for him or her to go into cardiac arrest.
Keep them horizontal and calm, and reassure them that they're going to be fine. Use each other's body heat to warm up by getting into a sleeping bag together or simply hugging each other tight to create warmth. And, of course, seek medical attention as soon as possible.

3: Wear a hat, despite the myth
You've probably heard the popular myth that you lose most of your body heat through your head. This myth was perpetuated by an outdated U.S. Army survival training manual that stated that 40% to 50% of our body heat is lost through the head. The truth is, you lose the same amount of heat through your head as you would any part of your body that is exposed to the elements However, you're way more likely to go out into the cold without a warm hat, than say, a shirt or a pair of shoes. But just because you don't lose more heat through your head doesn't mean you should leave your winter hat on the rack. Wearing a touque is a great way to assist your heavy coat, gloves, boots and snow pants in keeping all of you warm. Think of it as capping off your winter clothing plan.

 World Hot Topics Blog

4: Keep Hydrated
Hydration isn't just a warm weather worry. Many people forget that you need water in the freezing cold just as much as you do in hot weather. If your pipes are frozen, eating some snow or ice may seem like a great idea, but it will lower your core temperature and actually bring on dehydration. You can melt the snow or ice, but remember that while it can be safe to ingest in more remote locations, drinking water from melted "city snow" is a risk. You'll also want to avoid drinking only coffee or alcohol as a warming technique. I know this one is tough to resist since it may give you a short-term warm up, but it'll dehydrate you much more quickly. If you must indulge, remember to also drink plenty of water along with your coffee or toddy.

5: Light Your Fire
A fire is the best way to fight a winter chill if you're stuck in your home without power. And this means only fireplaces. You should never use your gas oven or stove to warm up under any circumstances as it could lead to carbon monoxide poisoning. But if you have a fireplace or a kerosene heater you're in luck. Use your fireplace as your main heat source, and if you can, sleep in the room with it — just not too close and with a protective fire screen. The last thing you want to do is wake up to find that fire has moved from the fireplace to your living room carpet.
If this vortex leaves you worried that winters could be severe in your part of the country from now on, before the next one, make sure you have a nice stockpile of wood, as it will be tougher to find once a storm hits, and outages can last days or weeks depending on how severe the weather is and how competent our utility company is in restoring power.
And here's a new summer task to consider: Make sure your chimney is clear and clean before the chimney sweeps are all booked up — and the next vortex swoops down from the north.

This World Hot Topics Blog is Originally from here :
http://edition.cnn.com/2014/01/07/opinion/bryant-cold-weather/index.html?iid=article_sidebar

Tuesday, May 14, 2013

Kids' chemical injuries down, but may rise in summer



World Hot Topics Blog

Kids' chemical injuries down, but may rise in summer

By Kerry Grens
NEW YORK (Reuters Health) - Injuries from gasoline, lamp oil and similar chemicals have dropped considerably among small children in the last decade, according to a new study.
"It seems to decline right around 2000, 2001. That's when the Consumer Products Safety Commission mandated products be placed in child-resistant packaging," said Dr. Heath Jolliff, the study's lead author and associate medical director of the Central Ohio Poison Center at Nationwide Children's Hospital in Columbus.

Summertime, however, brings extra risk for exposure to these types of poisonings, especially among toddlers.
 World Hot Topics Blog
"The kind of gasoline (used) with the lawnmowers, (fuel for) tiki torches and that sort of thing - because of the access, (children) get the exposure," said Dr. Jennifer Lowry, chief of Clinical Toxicology at Children's Mercy Hospital in Kansas City, Missouri.

Fuels such as lamp oil for tiki torches, kerosene for camping stoves and gasoline, as well as turpentine and some lubricants are all hydrocarbons - a category of dangerous liquids that is the third leading cause of children's poisoning deaths, Jolliff and his colleagues write in the journal Pediatrics.

"We had had a child in our hospital who had been exposed to a hydrocarbon and was very ill. And I said, 'let's look at this subcategory since they tend to be very dangerous,'" Jolliff told Reuters Health.

 World Hot Topics Blog

To get a sense of broader trends in injuries resulting from these chemicals, the researchers gathered information from two large databases spanning the 10 years from 2000 through 2009.
One database includes emergency department records from about 100 hospitals across the U.S. The other has phone calls made to 57 regional poison control centers.

The researchers narrowed down the records to only those involving hydrocarbons and children five years old and younger - which totaled more than 40,000 patients treated in an emergency room and more than 65,000 phone calls to poison control.

They found that emergency room visits dropped over the study period, from roughly 19 out of every 100,000 kids in 2000 to about 14 of every 100,000 in 2009.

 World Hot Topics Blog

Similarly, calls to poison control centers also fell, from 34 calls for every 100,000 kids in 2000 to about 21 of every 100,000 in 2009.

Injuries were most common among one- and two-year-olds, and kerosene, lamp oil and lighter fluids resulted in the most serious injuries and hospitalizations. Lamp oil was linked to the highest percentage of deaths.

Although the researchers could not determine why poisonings appeared to become less frequent over the 10-year study period, Lowry, who didn't participate in the research, thinks that child-resistant caps on poisonous containers likely helped.

In 2001, the Consumer Product Safety Commission required that all household products containing hydrocarbons be sealed with child-resistant packaging.

In addition, "there was a big educational push in the early 2000s on hydrocarbons and how dangerous they were," Lowry told Reuters Health.

Although injuries declined over time, summertime each year brought a slight bump in cases.
Nearly 32 percent of emergency room visits and poison control calls came during the summer months, compared with 19 percent of emergency room visits and 17 percent of poison control calls during the winter.

 World Hot Topics Blog

Gasoline was the most common hydrocarbon involved in an injury, Jolliff's team found.
Nearly 32 percent of emergency department visits and 27.6 percent of poison control center calls concerned gasoline.

When the researchers looked through the medical records at the hospitals, they found a surprising cause.

"The number one reason was parents allowing their kids outside the automobile at the gas station, and kids pulled the hose out of the car and got splashed with it," said Jolliff.
What happens then is that because the liquid becomes a gas so quickly, the children inhale it into their lungs.

"It's very unsafe for children five and under to be out there helping to pump gas," said Lowry.
Jolliff said that although child-resistant packaging helps keeps kids out of dangerous chemicals, there is no such thing as child-proof containers.

Another recent study found that prescription drug poisonings among children is on the rise (see Reuters Health story of September 16, 2011 here: http://reut.rs/qIUKP9).
"We have to do better education on placement. One of the poison center mottos is 'up and away.' Keep them out of reach of children," said Lowry.

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This World Hot Topics Blog is Originally from here :
http://bit.ly/16d4isN Pediatrics, online May 6, 2013.

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